KMID : 0363020050350040877
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Journal of Korean Academy of Periodontology 2005 Volume.35 No. 4 p.877 ~ p.889
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Clinical study on therpeutic effects of Guided tissue regeneration by Nanogide-C(R) and Biomesh(R) in furcation defects
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Abstract
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This study was designed to compare the effects of treatment using chitosan membrane
(Nanogide-C¨Þ) resorbable barrier with control treated by polylactic acid/polylacticglycolic acid
membrane(PLA/PLGA membrane, Biomesh
¨Þ). 44 furcation defecs from 44 patients with class 2
furcation degree were used for this study, 22 sites of them were treated by chitosan membrane
as experimental group and 22 site were treated by PLA/PLGA membrane as control group.
Clinical parameters including probing depth, gingival recession, attachment level and
radiographic examination were evlauated at base line, 1 month, 2 month and 3 month. after
surgery. Statistical test used to analyze these data included paired t-test, one way ANOVA.
The results are as follows :
1. Probing depth was significanlly decreased in the two group and there were significant
differences between groups(p<0.05).
2. Gingival recession was not significanlly increased in the two group and there were no
significant differences between groups(p<0.05).
3. Loss of attachment was statistically decreased in the two group and there were no
significant differences between groups(p<0.05).
4. Horizontal bone level was significanlly increased in the two group and there were
significant differences between groups(p<0.05).
On the basis of these results, chitoans resorbable membrane has similar potential to
PLA/PLGA membrane in GTR for furcation defect.2)
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KEYWORD
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chitosan membrane, PLA/PLGA, furcation involvement, GTR
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